Publications

  1. Chen Gao, Jianli Gong, Nancy Cao, Yibin Wang, Susan F. Steinberg, “Lipid-Independent Activation of a Muscle Specific PKCa Splicing Variant” American Journal of Physiology-Heart and Circulatory Physiology, 2022 Oct 1; 323(4):H825-H832 PMCID:PMC9550568
  2. Chen Gao, Yibin Wang, “Cardio-Protective Messengers From ‘Good Fat’”, Circ Res, 2022 May 12:130(10):1507-1509 PMCID:PMC9709701
  3. Yuliang Feng, Liuyang Cai, Wanzi Hong, Chunxiang Zhang, Ning Tan, Mingyang Wang, Cheng Wang, Feng Liu, Xiaohong Wang, Jianyong Ma, Chen Gao, Mohit Kumar, Yuanxi Mo, Qingshan Geng, Changjun Luo,Yan Lin, Haiyang Chen, Shuang-Yin Wang, Michael J. Watson, Anil G.Jegga, Roger A Pedersen, Ji-dong Fu, Zhao V.Wang, Guo-Chang Fan, Sakthivel Sadayappan, Yigang Wang,Siim Pauklin, Feng Huang, Wei Huang, Lei Jiang, “Rewiring of 3D Chromatin Topology Orchestrates Transcriptional Reprogramming and the Development of Human Dilated Cardiomyopathy”, Circulation, Apr 2022;145:1663-1683 PMCID: PMC9251830
  4. Zhiyu Dai, Jianding Cheng, Bin Liu, Dan Yi, Anlin Feng, Ting Wang, Lingling An, Chen Gao, Yibin Wang, Maggie M. Zhu, Xianming Zhang, You-Yang Zhao, “Loss of Endothelial Hypoxia Inducible Factor-Prolyl Hydroxylase 2 Induces Cardiac Hypertrophy and Fibrosis”, JAHA, Nov 2021, 10(22) PMCID:PMC8751916
  5. Chen Gao, Jiayu Yu, Yibin Wang, “Branched chain amino acids in cardiac growth and pathology-timing is everything”, J Mol Cell Cardiol, 2021 Oct;159:14-15 PMCID:PMC9107373
  6. Chen Gao, Nancy Cao, Yibin Wang, “Metal dependent protein phosphatase PPM family in cardiac health and diseases”, Cell Signal,2021 Sep;85:110061 PMCID: PMC9107372
  7. Chen Gao, Nancy Cao, Yibin Wang, “The coming of age for branched-chain amino acids”, J Cardiovasc Aging, May 2021, 1(2):10.20517 PMCID:PMC8459750
  8. Chen Gao, Yibin Wang, “mRNA Metabolism in Cardiac Development and Disease: Life After Transcription”, Physiol Rev, April 2020, 100(2):673-694 PMCID: PMC7327233
  9. Qin JJ, Cheng X, Zhou F, Lei F, Akolkar G, Cai J, Zhang XJ, Blet A, Xie J, Zhang P, Liu YM, Huang Z, Zhao LP, Lin L, Xia M, Chen MM, Song X, Bai L, Chen Z, Zhang X, Xiang D, Chen J, Xu Q, Ma X, Touyz RM, Gao C, Wang H, Liu L, Mao W, Luo P, Yan Y, Ye P, Chen M, Chen G, Zhu L, She ZG, Huang X, Yuan Y, Zhang BH, Wang Y, Liu PP, Li H, “Redefining Cardiac Biomarkers in Predicting Mortality of Inpatients With COVID-19”, Hypertension, 2020 Oct; 76 (4):1104-1112 PMCID:PMC7375179
  10. Chen M*, Gao C*, Yu J, Ren S, Wang M, Wann RM, Chuang DT, Wang Y, Sun H, “Therapeutic Effect of Targeting Branched-Chain Amino Acid Catabolic Flux in Pressure-Overload Induced Heart Failure”, J Am Heart Assoc, 2019 Jun 4; 8(11):e011625 PMCID:PMC6585363
  11. Olver TD, Edwards JC, Jurrissen TJ,Veteto AB, Jones JL, Gao C, Rau C, Warren CM, Klutho PJ, Alex L, Ferreira-Nichols SC, Ivey JR, Thome PK, McDonald KS, Krenz M, Baines CP, Solaro RJ, Wang Y, Ford DA, Domeier TL, Padilla J, Rector RS, Emter CA, “Western Diet-Fed, Aortic-Banded Ossabaw Swine: A Preclinical Model of Cardio-Metabolic Heart Failure”, JACC Basic Transl Sci. 2019 Jun24;4(3):404-421. Doi:10.1016/j.jacbts.2019.02.004 PMCID: PMC6610000
  12. Gao C, Ren SV, Yu J, Baal U, Thai D, Lu J, Zeng C, Yan H, Wang Y, “Glucagon Receptor Antagonism Ameliorates Progression of Heart Failure”, JACC Basic Transl Sci, 2019 Mar 13;4(2):161-172 PMCID: PMC6488764
  13. Hu J, Gao C, Wei C, Xue Y, Shao C, Hao Y, Gou LT, Zhou Y, Zhang J, Ren S, Chen J, Wang Y, Fu XD, “RBFox2-miR-34a-Jph2 axis contributes to cardiac decompensation during heart failure”, Proc Natl Acad Sci USA, 2019 Mar 26;116(13):6172-6180 PMCID:PMC6442575
  14. Marrocco V, Bogomolovas J, Ehler E, Dos Remedios CG, Yu J, Gao C, Lange S, “PKC and PKN in heart disease”, J Mol Cell Cardiol, 2019 Mar;128:212-226 PMCID:PMC6408329
  15. Lue Y, Gao C, Swerdloff R, Hoang J, Avetisyan R, Jia Y, Rao M, Ren S, Atienza V, Yu J, Zhang Y, Chen M, Song Y, Wang Y, Wang C, “Humanin analog enhances the protective effect of dexrazoxane against doxorubicin-induced cardiotoxicity”, Am J Physiol Heart Circ Physiol, 2018 Sep 1;315(3): H634-H643 PMCID:PMC6734085
  16. Gao C, Wang Y, “Untangle a Broken Heart via Janus Kinase 1”, Circ Res, 2017 Sep 1; 121(6): 589-590 PMCID:PMC5599179
  17. Gao C, Howard-Quijano K, Rau C, Takamiya T, Song Y, Shivkumar K, Wang Y, Mahajan A, “Inflammatory and apoptotic remodeling in autonomic nervous system following myocardial infarction”, PLoS One, 2017 May 18;12(5):e0177750 PMCID:PMC5436752
  18. Rau CD, Gao C, Wang Y, “Deconvolution of the Human Endothelial Transcriptome”, Cell Syst, 2016 Spe 28; 3(3):218-220 PMCID: PMC5394198
  19. Wang Z, Zhang XJ, Ji YX, Zhang P, Deng KQ, Gong J, Ren S, Wang X, Chen I, Wang H, Gao C, Yokota T, Ang YS, Li S, Cass A, Vondriska TM, Li G, Deb A, Srivastava D, Yang HT, Xiao X, Li H, Wang Y, “The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy”, Nat Med 2016 Oct;22(10):1131-1139 PMCID:PMC5053883
  20. Sun H, Olson KC, Gao C, Prosdocimo DA, Zhou M, Wang Z, Jeyaraj D, Youn JY, Ren S, Liu Y, Rau CD, Shah S, Ilkayeva O, Gui WJ, William NS, Wynn RM, Newgard CB, Cai H, Xiao X, Chuang DT, Schulze PC, Lynch C, Jain MK, Wang Y, “Catabolic Defect of Branched-Chain Amino Acids Promotes Heart Failure”, Circulation 2016 May 24;133(21): 2038-49 PMCID:PMC4879058
  21. Gao C, Wang Y, “Positive Role for a Negative Calcineurin Regulator in Cardiac Hypertrophy”, Hypertension, 2016 May; 67(5):841-2 PMCID:PMC4862578
  22. Gao C, Ren S, Lee JH, Qiu J, Chapski DJ, Rau CD, Zhou Y, Abdellatif M, Nakano A, Vondriska TM, Xiao X, Fu XD, Chen JN, Wang Y, “RBFox1-mediated RNA splicing regulates cardiac hypertrophy and heart failure”, J Clin Invest, 2016 Jan; 126(1):195-206 PMCID:PMC4701548
  23. Pan BF, Gao C, Ren SX, Wang YB, Sun HP, Zhou MY, “Regulation of PP2Cm expression by miRNA-204/211 and miRNA-22 in mouse and human cells”, Acta Pharmacol Sin 2015 Dec;36(12):1480-6 PMCID:PMC4816230
  24. Sun H, Gao C, Wang Y, “A H(a)rd Way to Adapt in Cardiac Hypertrophy”, Circ Res. 2015 Aug 28; 117(6):484-6 PMCID:PMC4582434
  25. Gao C, Wang Y, “Transcriptome complexity in cardiac development and disease- an expanding universe between genome and phenome”, Circ J, 2014;78(5):1038-47 PMCID:PMC4306672
  26. Foster WH, Langenbacher A, Gao C, Chen J, Wang Y, “Nuclear phosphatase PPM1G in cellular survival and neural development”, Dev Dyn, 2013 Sep; 242(9): 1101-9 PMCID:PMC4230483
  27. Gao C, Wang Y, “Global impact of RNA splicing on transcriptome remodeling in the heart”, J Zhejiang Univ Sci B, 2012 Aug; 13(8):603-8 PMCID:PMC3411092
  28. Zhou M, Lu G, Gao C, Wang Y, Sun H, “Tissue-specific and nutrient regulation of the branched-chain a-keto acid dehydrogenase phosphatase, protein phosphatase 2Cm (PP2Cm)”, J Biol Chem, 2012 Jul 6; 287(28): 23397-406 PMCID:PMC3390616
  29. Lee JH, Gao C, Peng G, Greer C, Ren S, Wang Y, Xiao X, “Analysis of transcriptome complexity through RNA sequencing in normal and failing murine hearts”, Circ Res. 2011 Dec 9; 109(12): 1332-41 PMCID:PMC3243366